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Saxenda (liraglutide): MHRA-approved
doi: 10.1038/s41401-022-00942-2
Aging and wound healing of the skin: A review of clinical and pathophysiological hallmarks
From REDEFINE-1: Nausea: 55% of CagriSema participants vs 12.6% with placebo Constipation: 30.7% vs 11.6% Vomiting: 26.1% vs 4.1% Discontinuation rate: 5.9% vs 3.5% placebo comparable to Wegovy (6.9%) and Zepbound (6.2%) The nausea rate (55%) is higher than the ~4045% typical for semaglutide alone
Clinical trials confirmed no IGF-1 elevation and no negative impact on glucose metabolism, even during 24-week treatment periods
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