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Nature 626:427434
The Pro-Gly-Pro C-terminal extension stabilises the peptide against enzymatic degradation
It is not a drug, food, cosmetic, or dietary supplement and has not been evaluated by the FDA
Therapeutic approaches include the administration of probiotics and prebiotics, dietary modulation, and even fecal microbiota transplantation, aiming to restore microbial homeostasis and dampen neuroinflammatory cascades [622, 623]
[3] Ondansetron demonstrates selective antagonism at the 5-HT3 receptor sites, which are believed to play a crucial role in the pathophysiology of nausea and vomiting responses
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