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More recent studies suggest that the blood concentration of trimethylamine N-oxide (TMAO), generated from trimethylamine-containing nutrients like dietary choline, rather than that of choline, might influence the risk of cardiovascular events (see Safety)

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Mistake 1: Shaking the vial during reconstitution This is the single most common mistake

Editor's note: This text-based course is a transcript of the webinar, GLP-1s and More: Pharmacology for Diabetes Mellitus and Other Endocrine Conditions, presented by Melissa Bednarek, PT, DPT, PhD, CCS

3.1 Alternative nutrient-sensing mechanisms Some nutrients stimulate intestinal hormone secretion independent of taste receptors, via pathways involving other GPCR or nutrient transporters (95, 96): Stomach: Calcium-sensing receptor (CaSR) and GPRC6A detect a broad range of amino acids and calcium, promoting gastrin and somatostatin release (89, 97)