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Rare but serious reactions can include severe allergic reactions, significant potassium changes, or severe hypoglycemia

Our approach involves adjusting medication doses to optimize blood sugar control while minimizing the risk of hypoglycemia

229 The most often used backbone modification method is PS modification, where the oxygen atom is replaced by sulfur

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The price discount required to achieve formulary positioning also varies: interchangeable biosimilars have sometimes achieved formulary placement at lower discounts because the payer values the operational ease of pharmacy-level substitution