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Segn las recomendaciones de la Academia Nacional de Medicina, los hombres deben consumir aproximadamente 3.7 litros y las mujeres 2.7 litros de agua total diariamente (incluyendo la proveniente de alimentos y todas las bebidas), aunque las necesidades varan segn el individuo, el clima y el nivel de actividad

10.1681/ASN.2005030306 107 MllerJ

Animal data is a necessary first step, but its far from sufficient on its own to draw conclusions about a drugs effectiveness and safety in humans

Trejo et al