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For optimal clinical results, administration should occur on the same day each week to facilitate the intended systemic steady-state levels
This process requires the involvement of protein disulfide isomerase (PDI), ER redox protein 1 (ERO1), and GRP78 chaperone protein
Whilst GLP-1 agonists are not licensed for treating depression and evidence remains preliminary, their effects on brain regions involved in mood regulation have sparked considerable scientific interest
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