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Whats more, a systematic review and meta-analysis published in the Journal of Clinical Medicine further confirmed this advantage, finding that tirzepatide produced meaningfully greater weight loss than semaglutide across both clinical trials and real-world data sets

For example, Yanai et al

Alexandra Sowa, an obesity medicine specialist and founder of SoWell, says she's seen many patients who ask for microdoses because of the stigma around using these drugs

The published trial reported its findings, but the compound has not been approved for human use

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