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That said, their simultaneous use should be approached with caution

"Randomized trial to evaluate the clinical benefits of serum alpha-glutathione S -transferase concentration monitoring after liver transplantation"

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Keller J, Couturier A, Haferkamp M, Most E, Eder K

Berberine's mechanism involves multiple pathways beyond GLP-1, including direct effects on glucose metabolism, gut microbiota modulation, and inflammation reduction