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Disease-associated mutants, in general, can produce hydrophobic patches in the protein due to local misfolding, which will result in aggregation 46,47,48
In rare cases: headache, dizziness, anxiety, or gastrointestinal disturbances
Discard if the solution becomes cloudy, loses its blue tint, or develops particulate
doi: 10.3389/fendo.2017.00280
Hypoxia induced lactate acidosis modulates tumor microenvironment and lipid reprogramming to sustain the cancer cell survival
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