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10.3390/ijms21072546 65 LibermanA.EsserM.MarxN.BurgmaierM
Chronic administration of high doses of oral levocarnitine in patients with severely compromised renal function or in ESRD patients on dialysis may result in accumulation of the potentially toxic metabolites, trimethylamine (TMA) and trimethylamine-N-oxide (TMAO), since these metabolites are normally excreted in the urine
the two large null dementia-prevention trials ( GEM , JAMA 2008 and GuidAge , Lancet Neurology 2012)
10.1016/j.diabres.2021.109119 67 TobaiqyM
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