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Hattori, S

doi: 10.1523/jneurosci.3006-19.2020 35

When evaluated after exposure to LASSS at a 1:8000 molar ratio to HGF and subsequent ultra-filtration to wash-out un-reacted free LASSS, c-met binding affinity increased more than two-fold over the original non-nitrated HGF

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Further, LAT1-dependent binding affinity was measured and calculated with or without the presence of the LAT1 inhibitor, 2-aminobicyclo-(2,2,1)-heptane-2-carboxylic acid (BCH)