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lavocat
It belongs to a class of drugs known as GLP-1 receptor agonists, designed to mimic the actions of a hormone called glucagon-like peptide-1 (GLP-1) in the body
In the STEP 1 trial (NEJM, 2021), semaglutide 2.4mg achieved a mean weight reduction of 14.9% over 68 weeks versus 2.4% placebo establishing a benchmark that subsequent compounds including retatrutide have sought to surpass
Patients treated with semaglutide experienced lower hospitalization rates for any cause compared with placebo, as well as fewer admissions related to serious adverse events
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