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Folate supplementation without adequate B12 can also partially mask B12-related anaemia in routine blood tests, making deficiency harder to detect through a standard CBC alone (Cikot et al., 2001, British Journal of Nutrition)
1 2 The American Journal of Clinical Nutrition
Cardiovascular effects on blood pressure and vascular tone require monitoring, particularly in patients with existing cardiovascular disease or those taking cardiovascular medications
Additional benefits include metabolic enhancement without growth hormone side effects, no impact on blood glucose or insulin sensitivity, potential increases in energy expenditure through thermogenic mechanisms, and compatibility with athletic training and performance goals
It is typically used to counteract the harmful effects of methotrexate, a common chemotherapy drug
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