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Rather unexpectedly, this twincretin, a single molecule providing high-affinity activation of two incretin hormone receptors, is substantially more effective in normalizing blood sugar, and in reducing body weight, when compared to traditional GLP-1 receptor agonists just addressing the GLP-1 receptor

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Liver function tests should be obtained at baseline, after 6-8 weeks during niacin dose titration, and periodically thereafter

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This can reduce energy fluctuations and support more consistent activity throughout the day