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You should call your doctor immediately or seek emergency medical attention if you develop: Serious allergic reaction: swelling of the face, tongue, or throat, shortness of breath, hives, rash, and itchiness Low calcium levels: Numbness or tingling in the fingers, toes, or around the mouth Muscle cramps, spasms, twitching, or stiffness Unusual skin problems: Redness, dryness, itching, peeling, oozing, blistering, warmth, swelling, or tenderness of the skin Newly developed pain in the hip and thigh area Has anyone had bad side effects from Prolia

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If the solution is cloudy or contains visible particles after 5 minutes of gentle swirling, the peptide may be degraded