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People and mice differ in metabolism, body size, route exposure, and disease biology, so animal results cannot predict a person's outcome
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The dosing volume for vitamin B12 injections can significantly differ based on whether the regimen is weekly or monthly, impacting the overall treatment plan. Its important for both doctors and patients to know these differences
However, the largest Phase IIb trial involving 536 subjects failed to demonstrate statistically significant weight loss compared to placebo at the primary 12-week endpoint, leading Metabolic Pharmaceuticals to terminate development in 2007
If low B12 damages this sheath, nerve signals can misfire, leading to symptoms like tingling, numbness, or that awful pins and needles feeling
