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Animal experiments All animal procedures were performed in accordance with the ethical standards approved by the Animal Care and Ethics Committee of the Second Affiliated Hospital, Zhejiang University School of Medicine

Affiliation: Department of Pharmacology, Toxicology & Therapeutics, University of Kansas Medical Center, Kansas City, KS 66160, USA Email: [email protected] ORCID: Affiliation: Department of Pharmacology, Toxicology & Therapeutics, University of Kansas Medical Center, Kansas City, KS 66160, USA ORCID: Explor Dig Dis

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However, those at low temperature increased immediately

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