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Functional studies on the enzyme have identified an N-terminal lipid-binding region, the / hydrolase fold domain including the catalytic triad, and the regulatory module containing all known phosphorylation sites important for regulation of enzyme activity

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Intracellular ROS measurement LNCaP cells were seeded at 6 10 4 cells/well in 24-well plates, adhered overnight and then incubated with conditioned media for 2.5 days before treatment with doxorubicin or taxol

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DIM has shown an ability to metabolize excess estrogen, which can be helpful for people with estrogen dominance or other hormone imbalances making it one of the best vitamins for hormonal acne