The dosing typically starts low and gradually increases over several weeks to minimize side effects and allow your body to adjust to the medication
Short-term administration of the GLP-1 analog liraglutide decreases circulating leptin and increases GIP levels and these changes are associated with alterations in CNS responses to food cues: A randomized, placebo-controlled, crossover study
While effective, this approach carries risks including supraphysiological hormone levels, suppression of natural GH production, and side effects such as fluid retention, joint pain, carpal tunnel syndrome, and potential insulin resistance
Lingvay I, Catarig AM, Frias JP (2019) Efficacy and safety of once weekly semaglutide versus daily canagliflozin as add-on to metformin in patients with type 2 diabetes (SUSTAIN 8): a double-blind, phase 3b, randomised controlled trial
Some users may experience side effects such as nausea, fatigue, or gastrointestinal discomfort, especially when starting GLP-1 medications or oral kits