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Seiwerth and colleagues (Inflammopharmacology, 1999) documented effects on angiogenic growth factor pathway signalling, and subsequent work has expanded characterisation to include VEGF receptor 2 upregulation, endothelial cell migration in capillary-formation assays, and improved healing in ischemia-reperfusion preparations
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Additionally, since peptides are natural compounds, results can vary depending on the individuals condition and response to treatment
Therefore, there is a very low risk of B12 toxicity, even at high doses like 1,000 mcg a day
Supports musculoskeletal angiogenesis research and repair signaling
