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First, although we clearly demonstrated that IGF-1 attenuated cardiac fibrosis in an AngII-infusion mouse model, cardiac fibrosis is already present in pathological conditions, such as hypertension or myocardial infarction, when antifibrotic treatment is started in humans
FDA approved the first generic drug containing liraglutide in December 2024
GLP-1 RA therapy significantly improved both exercise capacity and HRQoL in individuals with obesity-related HFpEF regardless of diabetes status, but had no effect on these parameters in in HFrEF patients
F.et al (2024)
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