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We further demonstrated that CoQ 10 H 2 inhibited transcriptional activity of the transcription factor AP-1 and that of C-FOS, a component of AP-1, and that CoQ 10 H 2 inhibited the ability of AP-1 to bind to the PDE4 gene promoter (Fig

Animal Studies: Strong Results in Obese Rodent Models The foundational animal work was conducted in obese Zucker rats and ob/ob mice, two standard models for studying obesity

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