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The net charge (Z) sums the contributions from positive charges of the N-terminus, arginine, lysine, and histidine residues, and negative charges of the C-terminus, aspartic acid, glutamic acid, cysteine, and tyrosine residues

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The practical rule: use a U-100 syringe for semaglutide, tirzepatide, and similar compounded peptides reconstituted at 1 mg/ml

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