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Glutathione is a naturally occurring antioxidant that plays a role in cellular processes such as detoxification and oxidative stress response
These deleterious signaling cascades converge on mitochondria, where membrane-potential loss, electron-transport dysfunction, and mitochondrial permeability transition pore opening (mPTP) promote cytochrome c release and cell death [2,3,4,5,6,7,8]
[4] [5] Readers should note that these figures reflect specific trial protocols and may not represent the doses used in ongoing phase 3 studies or any future licensed product
It cannot be transported in/from plasma or stored within the cell as cysteine, as it would rapidly autooxidize to cystine, producing potentially dangerous oxygen radicals
