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doi: 10.1016/j.cmet.2016.06.009 38 ChenJXuSZhouWWuLWangLLiW

Akatsuka et al., 2012) and multi-walled carbon nanotube-induced (Nagai et al., 2011) mesothelial carcinogenesis in wild-type rats are the models that confer massive chromosomal alterations including homozygous deletion of Cdkn2a/2b