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In a phase 1b placebo-controlled, randomized clinical trial, participants with overweight or obesity received OW SC cagrilintide at various doses or placebo, in conjunction with semaglutide 2.4 mg over 20 weeks [123]
Namely, we fed C57BL6/J mice a chow (Chow) or high-fat, fructose, cholesterol (FFC) diet and co-administered either saline or EtOH
* Fertility procedures were defined broadly to include claims related to insemination, embryo transfer, in vitro fertilization and related lab procedures, egg retrieval, fertility testing and monitoring, and other assisted reproduction services
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In contrast, exenatide appeared to worsen drinking outcomes in lean individuals, suggesting that body weight may influence treatment response
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