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For drug developers, the deal signals growing pharma investment in overcoming the manufacturing and cost bottlenecks that have limited traditional ex vivo cell therapies, potentially widening patient access to CAR T approaches beyond oncology
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Collectively, our findings indicate that SO286 inhibited -syn aggregation by inhibiting both the -synUBQLN2 interaction and the liquidgel/solid phase transition of UBQLN2 droplets
Autophagy 18 , 17401742 (2022)
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