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Its also possible that a crash follows the initial boost of energy as the body adjusts to the sudden influx of B12

Site Rotation: Rotate systematically between injection sites (abdomen at least 2 inches from navel, outer thighs, upper arms, upper buttocks) to prevent lipohypertrophy and local irritation [14]

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It also suggests getting five or six injections bi-weekly to load the body

References (1) Thakkar K1, Billa G2