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HLA-B*58:01 for allopurinol-induced cutaneous adverse drug reactions: implication for clinical interpretation in Thailand

doi:10.1001/jamanetworkopen.2025.2281

Inflammatory cytokines blunt GLP-1 receptor responsiveness and destabilize insulin signaling, contributing to metabolic relapse

GLP-1 receptor agonists (semaglutide, liraglutide) increase gallbladder event rates compared to placebo, primarily due to rapid weight loss rather than the medication itself

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