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Zuo RC, Apolo AB, DiGiovanna JJ, Parnes HL, Keen CM, Nanda S
The study of epigenetics is gaining momentum as a plausible means of theragnostic application which can be easily extended to the discovery of epi-drugs that relate to the epigenome of DCM pathogenesis
It takes 4 to 8 weeks before results (if any) are seen
When someone is experiencing hormonal imbalance or insulin resistance, though, this can mess with the bodys ability to do this conversion, causing the ratio to be off
So, in summary: FOXO4-DRI appears to represent the next-generation senolytic, offering improved specificity, but it is still earlier stage than many small-molecule senolytics or repurposed drug combinations
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