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Methods to deliver iron chelators to the CNS include direct (such as intranasal and intrathecal) and indirect (such as oral and injections) routes (Figure 1) (Rohani et al., 2017
Studies suggest that lowering NNMT levels may help counteract some of the mechanisms underlying impaired stem cell function in these disorders
Altogether, these data will have to be firmly established by complementary experiments, especially if a cleavage could also generate soluble isoforms
Additionally, unlike male birds, female birds treated with BSO during development exhibited longer telomeres, increased growth, and greater body mass than control females in adulthood [45]
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