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sitagliptin Sitagliptin Trade Name: Januvia Drug Class: oral hypoglycemics Mechanism of Action: An inhibitor of dipeptidyl peptidase-4 (DPP-4), a protease that degrades the incretin GLP-1 Incretins are hormones released from the GI tract in response to nutrient ingestion Incretins potentiate glucose-stimulated insulin secretion from beta cells in the pancreas As a result of inhibiting DPP-4, increased or prolonged GLP-1 levels are able to potentiate the secretion of insulin by the pancreas The effect produced by DPP-4 inhibitors is dependent on endogenous GLP-1 levels, and produce a modest effect on GLP-1 activity compared to giving GLP-1 receptor agonists (hence DPP-4 inhibitors do not have the same impact to produce weight loss as GLP-1 agonists)
Frequently Asked Questions: Wegovy Pen Safety In adult weight-management clinical trials, nausea was the most reported side effect of the Wegovy pen
Here are some common inquiries regarding this treatment
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The Top Nutrients GLP1 Users May Be Lacking Vitamin D3 Vitamin D deficiency stood out as the most frequently diagnosed problem in GLP1 users across several studies
