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Bariatric surgery offers lasting weight loss and metabolic health improvements without ongoing medication
These can cause rapid spikes in blood sugar levels, making diabetes management more difficult
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The SELECT trial established cardiovascular risk reduction in overweight adults without diabetes, while the STEP HFpEF program showed symptomatic improvement in heart failure with preserved ejection fraction [2]
This ferroptosis-induced pancreatic cancer development could be linked to macrophage infiltration and polarization, mediated by the release of 8-OHG (8-hydroxy-2-deoxyguanosine) resulting from ferroptotic damage and subsequent activation of the STING1-dependent DNA sensor pathway [209, 210]
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