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Histologic evidence from massive weight loss demonstrates increased elastic fiber density compared to morbidly obese skin, but altered collagen architecture and decreased dermal thickness are common, which can translate to visible laxity even if elastic fibers are on the rise

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384, 10 Feb

Moreover, it plays an immune negative regulatory role in chronic hepatitis B virus (HBA) infection by preventing the formation of germinal centers (GCs), reducing the antiviral activity of GC-related immune cells and enhancing the function of immunosuppressive cells [227]