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Additionally, recent studies have found that the expression of GPX4 and GSH was disordered in rats administered DOX [92]
Zakariassen, H
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Particular attention has been directed toward MC1R- and MC4R-associated pathways , which are implicated in the regulation of inflammatory responses, autonomic balance, and tissue resilience during ischemic stress conditions [11,12]
In addition, there is considerable evidence that estrogen increases substantially the activities of GPX and Glutamate Cysteine Ligase (GCL), an enzyme in the GSH pathway [5-7]
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