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In trial 1, the mean change in AHI at week 52 was a reduction of 25.3 events per hour with tirzepatide, compared to a reduction of 5.3 events per hour with placebo, resulting in a treatment difference of -20.0 events per hour (95% CI, 25.8 to 14.2
This is true for all semaglutide formulations, methylcobalamin or not
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AI and AI-assisted tools statement During the preparation of this manuscript, the AI tool ChatGPT (GPT-5, released 2025-08-07) was used to generate Figure 1 and the Graphical Abstract and to improve the readability and language of the manuscript
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