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Patients who switched from semaglutide to orforglipron maintained a mean 79.3% of their body weight reduction compared with the placebo arm which maintained a mean 37.6% of their weight loss
Without the drug, appetite returns
33 In a randomized, double-blind, placebo-controlled trial involving patients with MASH, treatment with NGM282 (an engineered FGF19 analog) for 12 weeks led to rapid and significant reductions in liver fat content, ALT, AST, and serum markers of fibrogenesis
Novo market share continues to get eaten by Lilly both US and worldwide
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