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Results are inconsistent and slow 1

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So, although the DMSA treatment appeared to be beneficial in most cases, there was a small subset whose symptoms appeared to worsen slightly

ACTL6A impacts GSH de novo synthesis mainly by upregulating -glutamyl-cysteine synthesis To further assess the mechanism by which ACTL6A regulates GSH metabolism, we investigated the metabolic fate of U- 13 C glucose by liquid chromatography with mass spectrometry (LCMS), which produces -GC containing two 13 C atoms via GSH de novo synthesis pathway, GSH containing two 13 C atoms via GSH de novo synthesis or the SGOC pathway, or four 13 C atoms via both pathways (Fig

Current research is encouraging, but there are still important questions that only larger human studies conducted over longer periods will be able to answer