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After 72 weeks, participants taking 7.2mg lost an average of 18.7% of their starting body weight, compared with 3.9% in the placebo group

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For example, people with diabetes may see more noticeable improvements in blood sugar control, while those with kidney issues may need a lower dose or more monitoring

Research suggests the largest improvements often occur in individuals who: Have obesity Have hypertension before starting treatment Lose a substantial amount of weight Have insulin resistance Have metabolic syndrome Improve their nutrition and exercise habits People with higher baseline blood pressure readings generally experience greater reductions than those whose blood pressure is already within a healthy range