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NNMT expression increases significantly with obesity and aging, particularly in white adipose tissue and skeletal muscle
For deficiency without neurological involvement or for borderline levels, oral supplementation with high-dose cyanocobalamin (1000-2000 mcg daily) is often effective, as approximately 1% of an oral dose is absorbed through passive diffusion even in the absence of intrinsic factor
Thankfully, the risk of B12 side effects is low
Perfect for research and pharmaceutical applications
We only use premium, pharmaceutical grade methlycobalamin B12 manufactured in Germany
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