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It signals your pituitary to make and release your own growth hormone

Beyond hormonal changes, several interconnected factors may contribute to perimenopausal weight gain: Metabolic slowdown : Basal metabolic rate naturally decreases with age, meaning the body burns fewer calories at rest Muscle mass loss : Sarcopenia (age-related muscle loss) accelerates during perimenopause, further reducing metabolic rate Sleep disruption : Night sweats and insomnia, common perimenopausal symptoms, interfere with hormones regulating appetite and glucose metabolism Mood changes : Anxiety, depression, and stress during this transition may lead to emotional eating patterns Reduced physical activity : Fatigue, joint pain, and other symptoms may decrease exercise tolerance Research suggests women may gain weight gradually during perimenopause, though individual experiences vary considerably

But for sure, the way it works with certainly some other drugs is that good Rx does the thing [00:18:41] where they go around and they shop all the PBMs and find the lowest cash price that any given PBM will accept

Fat on the intestines can only be diminished by weight loss through diet and exercise

However, drug interaction data from other medications that slow gastric motility suggests theoretical risk exists