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The mutants exhibited a significant effect on the nanobodies stability, as evidenced by the Cartesian ddG values ranging from -8.9 kcal/mol to 63.8 kcal/mol for PV2 and 9.4 kcal/mol to 73.3 kcal/mol for PV3
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In addition, the skins structural support does not always readjust to the same extent once underlying volume has decreased, particularly when changes occur over a shorter period
Smaller meals mean less stool volume and less stimulus to go
doi: 10.1016/j.immuni.2009.02.009 199 Van RoyenTRosseyISedeynKSchepensBSaelensX
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