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Ipamorelin# Ipamorelin (Aib-His-D-2-Nal-D-Phe-Lys-NH2) is a pentapeptide that also acts through GHS-R1a but with a binding profile that produces clean, selective GH release
Kraft, M., et al
Key nutrients to prioritize: Protein to protect muscle mass Fiber (2530 g/day for women) to support fullness and prevent constipation Hydration Micronutrients such as calcium, iron, and vitamin D Hormonal shifts can further influence digestion and metabolism, particularly in women navigating overlapping conditions such as PCOS and perimenopause, explored in The PCOSPerimenopause Connection
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In the short-term this could help to mitigate the increase of nausea and vomiting we observed at peak estrogen levels, and thereby reduce discontinuation rates in women, which are higher than in men
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