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Pfizer plans to submit global regulatory filings seeking approval in adults with nonsegmental vitiligo, a condition that currently has no approved oral systemic treatment

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It also indirectly reduces oxidative stress by regenerating vitamins C and E and acting as a cofactor for other antioxidants in the body

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306 Intrinsic nuclear PD-L1 can also cooperate with p-STAT3 to upregulate IL-6, activating MDSCs through the IL-6/JAK/STAT3 axis in a PD-1independent manner