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While animal safety data is extensive and positive, no clinical safety data in humans has been published
If you want the background on the amylin side first, our explainer on what cagrilintide peptide is used for covers its development history, and our compounded tirzepatide guide explains why approved, compounded, and research-grade products are not the same category
Another 16-week phase 2 trial in subjects with T2D and BMI 2550 kg/m 2 treated with survodutide 0.3, 0.9, 1.8, 2.7 mg weekly, 1.2 mg and 1.8 mg twice weekly, compared to semaglutide 1.0 mg weekly or placebo shows mean HbA1c percentage point reductions of 0.9, 1.5, 1.7, 1.6, 1.6, 1.7, 1.5, and 0.2, respectively, as well as mean body weight reductions significantly greater than placebo at all treatment doses, the highest being 8.7% for the 1.8 mg twice a week dose (97)
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