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doi: 73
When activated by Mounjaro, these receptors slow gastric emptying the rate at which food moves from the stomach into the small intestine
Pharmacological GLP-1RA Action Key Mechanistic Distinctions A comprehensive review published in Cell Metabolism reviewed circuits engaged by endogenous versus pharmacological GLP-1 action, highlighting key GLP-1R-positive cell types and pathways transducing metabolic and non-glycaemic GLP-1 signals
Thursdays approval marks the first treatment for this patient population
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