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Variants in GLP1R (one of tirzepatide's two receptor targets), FTO (fat-mass and obesity-associated), MC4R (satiety and energy balance), and TCF7L2 (glucose homeostasis and incretin secretion) map the baseline terrain
J Surg Educ 66(5):248-54, 2009
Lock D, Designing for user engagement in medical technologies a framework people want to use
The result: reduced hunger, improved blood sugar control, and significant weight loss
Original research focused primarily on those with diabetes, but a recent study found an increased risk of stomach paralysis for non-diabetic patients who used medications like Ozempic, Wegovy, Rybelsus, and Saxenda for weight loss
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