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This suggests the mechanism involves direct neurochemical effects rather than secondary consequences of improved metabolic health or self-esteem

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Two other pharmaceutical companies have their own oral GLP-1 drugs in the works: Orforglipron: Developed by Eli Lilly, its in Phase 3 clinical trials for treating type 2 diabetes and obesity, with an expected September 2025 completion

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doi:10.1016/0014-5793(95)01070-U