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Significance was expressed in terms of P value, which was considered significant when it was less than or equal to 0.05

Section Summary: L-carnitine is a naturally occurring amino acid derivative that plays a critical role in cellular energy production by transporting fatty acids into the mitochondria

Traditionally valued for supporting healthy energy metabolism, promoting natural physical endurance, and contributing to overall vitality during daily exercise and activity, L-Carnitine Tartrate is one of the most widely used and well-researched ingredients in active wellness nutrition

SIRT6 downregulation inhibits Nrf2 activation, whereas sirtuin 6 (SIRT6) upregulation reduces oxidative stress-associated DNA damage and promotes hepatocyte proliferation, thereby preventing APAP hepatotoxicity (Zhou et al., 2021)