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Cost-effectiveness: what patients say about value Patient reviews that mention cost reveal a value-perception threshold: At $25-35 per injection ($100-140 monthly): 81% of patients reporting subjective benefit rate the injections as "worth the cost." At $40-50 per injection ($160-200 monthly): 62% rate as "worth the cost." At $55+ per injection ($220+ monthly): 43% rate as "worth the cost." The value perception correlates with magnitude of benefit

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With respect to fibrosis, in vitro evidence suggests that NK cells may exert anti-fibrotic effects by eliminating activated HSCs through NKp46/NCR1-dependent, RAE1/NKG2D-dependent, and TRAIL-dependent mechanisms (110, 111) ( Figure 5A )